KMID : 1137020160270020021
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Journal of Gynecologic Oncology 2016 Volume.27 No. 2 p.21 ~ p.21
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Clinical significance of human papillomavirus genotyping
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Choi Youn-Jin
Park Jong-Sup
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Abstract
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Cervical cancer is the fourth most common cancer in women worldwide, and the human papillomavirus (HPV) is the main causative agent for its development. HPV is a heterogeneous virus, and a persistent infection with a high-risk HPV contributes to the development of cancer. In recent decades, great advances have been made in understanding the molecular biology of HPV, and HPV¡¯s significance in cervical cancer prevention and management has received increased attention. In this review, we discuss the role of HPV genotyping in cervical cancer by addressing: clinically important issues in HPV virology; the current application of HPV genotyping in clinical medicine; and potential future uses for HPV genotyping.
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KEYWORD
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DNA Tests, Genotype, Human Papillomavirus, Uterine Cervical Neoplasms, Vaccine
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